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Endocrine Surgery |
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Warning:If
you have any of the below problems and have
not been checked for the specified endocrine
cause, you should consult an endocrinologist.
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Brittle
and painful bones and urinary stones
may be due to excess parathyroid hormone |
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Fluctuating blood
pressure and anxiety attacks may be
due to adrenal and other neuroendocrine
tumors |
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Fits and episodes
of unconsciousness when hungry, may
be due to an insulinoma rather than
a form of epilepsy |
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Acidity and persistent
or recurrent stomach ulcers may be
due to gastrinoma |
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Obesity may be
due to Cushing’s disease or
thyroid deficit |
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Weight loss may
be due to excess thyroid. |
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What
are the causes of Goiter? |
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Thyroid swelling
can be due to tumors, iodine
deficiency, autoimmune (self
destructing) conditions, infection,
etc. |
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What
are the ill effects of
Goiter? |
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Thyroid
swellings can compress
the vital structures under
it like the gullet, breathing
tube, speech nerves, etc.
causing difficulty in
swallowing, breathing,
speech, etc.
There may be excessive
or decreased production
of thyroid hormone.
If there is cancer it
can spread and produce
problems in other parts
of the body. |
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How do you
test a Goiter? |
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Ultrasound scan,
FNAC (Fine Needle Aspiration Cytology),
Thyroid function tests, Anti thyroid
antibodies assay etc. are done. When
required, Radio isotope scan, CTscan
of neck and chest, MRI scan, blood
tests for cancer markers may be done. |
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How is a Goiter
treated? |
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Depending on the
cause it is treated with appropriate
medicines, radioactive iodine and
surgery to remove the whole thyroid
(Total Thyroidectomy) or half of it
(Hemi Thyroidectomy) or part of it
(partial/subtotal Thyroidectomy/lobectomy/Isthumusectomy).
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What are the
types of anesthesia and surgery for
Goiter? |
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Thyroid surgery
can be done under local, regional
or general anesthesia, with a 7 to
10cm cut across the neck by open surgery
or when feasible through a small less
than 3 cm skin cut by endoscopic (minimally
invasive) surgery. |
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What are the
risks of thyroid surgery? |
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Possible risks
include: 1) bleeding that can cause
acute breathing difficulty, 2) hoarseness
due to injury to the speech (recurrent
laryngeal) nerve, and 3) damage to
the parathyroid glands that control
calcium levels in the body, causing
hypoparathyroidism. The overall risk
of complications should be <2%
with an experienced surgeon. |
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What can I
do before thyroid surgery to be optimally
prepared? |
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It is important
that you do not eat or drink anything
after midnight the night before surgery.
Continue to take all important medications
such as heart, asthma, or blood pressure
medicines as advised by your anesthesiologist
with a small sip of water on the morning
of surgery. Diabetic medicines are
not taken by mouth on the day of surgery.
Do not take blood thinning drugs or
aspirin for 7-10 days prior to your
surgery date. Quit smoking. |
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Will I have
pain? Will I have stitches? What can
I expect after surgery? |
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You will be asleep
during your surgery and will feel
no pain. Pain after surgery is easily
suppressed by prescribed medicines.
Stitches placed under the skin are
not visible and dissolve after a period
of time and do not need to be removed.
You might have a sore throat, difficulty
swallowing, or a slightly hoarse voice
after the operation. These conditions
will resolve with time. There may
be a tube (surgical drain) in the
incision in your neck (which will
be removed the morning after the surgery).
Once you are fully awake, you will
be moved to a bed in a hospital room
where you will be able to eat and
drink as you wish. Most patients having
thyroid operations are hospitalized
for about 24 to 48 hours. Near normal
activity can begin on the first day
after surgery. You will have some
difficulty with full range of movement
of your neck for one week after surgery.
You can return to work in 1-2 weeks
time. Vigorous sports should be delayed
for at least 1 month. You may experience
low blood calcium (hypocalcaemia).
You may need to take Thyroid hormone
(Thyroxin) tablets, calcium and vitamin
D after surgery, sometimes lifelong.
During your follow-up visit, your
TSH (thyroid stimulating hormone)
levels will be checked and Thyroxin
dose adjusted accordingly. |
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What are the
signs of low blood calcium and how
will I know if I need to take extra
calcium? |
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Low blood calcium
occurs if the parathyroid glands (behind
the thyroid gland) do not function
properly. Symptoms of low blood calcium
include numbness and tingling in the
fingers and around the mouth, weakness,
headaches, muscle cramps, intestinal
cramps, heart arrhythmia (rhythm disturbance).
Low blood calcium can be prevented
or treated with extra calcium intake.
Left untreated, very low calcium levels
can cause chocking. |
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Will I have
a scar? |
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All surgeries cause
some scarring. When performed by skilled
endocrine surgeons, the thyroid operation
will be performed using the smallest,
cosmetically placed incision possible.
Plastic surgery type closures are
used to minimize scarring. Ultimately
the type of scar formed depends mostly
on the type of your body response
to any injury. The majority of people
having thyroid surgery have minimal
scar present by 6 months after surgery |
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How is thyroid
cancer treated? |
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It is treated by
surgery to remove the entire thyroid
(Total Thyroidectomy) and certain
adjoining tissues (depending on the
type of cancer and extent of spread).
This is followed by radioactive ablation
(RAI) i.e. destruction of any residual
thyroid or cancer with radioactive
isotope of iodine as Iodine is preferentially
taken up by thyroid tissue from the
blood stream. Thyroid hormone (Thyroxin)
tablets have to be taken daily, life-long.
Regular check up (may include scans,
blood tests for TSH, Thyroglobulin,
calcitonin, etc.) is essential to
detect any recurrence early. |
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What is the
outlook or prospects (prognosis) for
patients with thyroid cancer? |
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The outlook for
patients with thyroid cancer is excellent
in that safe and effective therapy
is available in most cases. Even those
patients whose thyroid cancer cannot
be cured, can usually live a long
time and feel well despite their cancer. |
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Parathyroid
Swelling (Adenoma, Hyperplasia, Carcinoma)
- Hyperparathyroidism |
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What
is Parathyroid? |
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Parathyroids
are four tiny glands hidden
near the thyroid gland in the
neck. They produce and release
parathyroid hormone which controls
the calcium levels throughout
the body. Excess production
of parathyroid hormone (PTH)
by abnormal parathyroid gland(s)
is called Hyperparathyroidism |
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What
happens in Hyperparathyrodism
(parathyroid excess)?
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Kidney
stones, bone pains, bone
cysts and swellings, joint
swellings, peptic ulcer
pain made worse by antacids,
weakness, fatigue, and
depression can be due
to hyperparathyroidism. |
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How do you test for
it? |
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This
can easily be detected by checking blood
for serum calcium and PTH (Para thyroid
hormone),both of which will be abnormally
high. It can then be localized by ultrasound
scan and Technetium Tc 99m Sestamibi scan
(See
Image). |
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Why
is treatment important? |
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Left
untreated bones become weak and break easily.
Kidney stones keep growing and reforming
after removal, ultimately damaging the kidneys. |
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How is Hyperparathyroidism
treated? |
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Treatment
requires surgical removal of the abnormal
parathyroid gland(s). Usually there is a
single parathyroid adenoma and it needs
to be identified and removed (Parathyroidectomy).
Occasionally there may be more and these
need to be detected and removed. Sometimes
one adenoma is dominant, and other adenomas
may become obvious later.
If there is hyperplasia, all glands except
half a parathyroid gland are removed. It
is preferable to transplant this half into
an easily assessable muscle in the neck
or forearm so that if it grows excessively,
parts of it can be removed easily.
For parathyroid cancer, the adjacent half
of the thyroid gland is removed (Hemi Thyroidectomy)
in addition to the parathyroid cancer. |
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What
are the types of anesthesia and surgery
for parathyroid adenoma removal? |
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Parathyroid
surgery can be done under local, regional
or general anesthesia.
Traditionally a large 7 to 10cms cut is
made across the neck and the entire front
side of the neck is searched for these four
tiny parathyroid glands by an experienced
surgeon. The Technetium Tc 99m Sestamibi
scan (a radio-isotope scan) has revolutionized
the identification and treatment of abnormal
parathyroid glands. The use of this radio-isotope
scan and the ultrasound scan has made minimal
surgery possible for parathyroid adenoma.
There are many methods of minimally invasive/
endoscopic surgery for the removal of parathyroid
adenoma. These techniques (totally endoscopic,
video assisted and radio guided) have been
demonstrated to be feasible and safe, but
it depends on the surgeon to obtain the
best results with these approaches. The
surgery can be done through a single cut
less than 3 cm or through three to four
5mm cuts in the armpit and breast. A specialist
endoscopic & endocrine surgeon (a rare
species!) would be conversant with all the
open and endoscopic methods and offer you
all the possible options. ENT/ Head &
neck surgeons, surgical oncologists, general
surgeons, laparoscopic surgeons also operate
on the parathyroid gland(s), each by the
method they are familiar with.
Complications are rare under the expert
care of an experienced endocrine surgeon.
The success of the procedure can be determined
soon after and the patient is fit to go
home in a few hours though we advise our
patients to stay till the calcium levels
stabilize a bit. |
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Will
I have pain? What can I expect after surgery? |
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Mild
pain after surgery is easily suppressed
by prescribed medicines. You might have
a sore throat, difficulty swallowing, or
a slightly hoarse voice after the operation.
These conditions will resolve with time.
Once you are fully awake, you will be moved
to a bed in a hospital room where you will
be able to eat and drink as you wish. Near
normal activity can begin on the first day
after surgery. You may have some difficulty
with full range of movement of your neck
for a week after surgery. You can return
to work in a few days time but be careful
with your brittle bones. Vigorous activities
and sports should be delayed as the bones
weakened by the parathyroid problem take
time regaining there strength. You may experience
low blood calcium (hypocalcaemia). You will
need to take calcium and vitamin D tablets.
During your follow-up visit, your Calcium
levels will be checked and medication dose
adjusted accordingly. |
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What
are the signs of low blood calcium and how
will I know if I need to take extra calcium? |
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Symptoms
of low blood calcium include numbness and
tingling in the fingers and around the mouth,
weakness, headaches, muscle cramps, intestinal
cramps, heart arrhythmia (rhythm disturbance).
Low blood calcium can be prevented or treated
with extra calcium intake.Left untreated,
very low calcium levels can cause chocking.
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Insulinoma
& Neuro endocrine tumors |
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What is Insulinoma?
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Insulinoma
is a tiny insulin hormone producing
tumor in the pancreas, an organ for
digestion located behind the stomach.
The excess insulin hormone dangerously
lowers the blood sugar levels. This
is the opposite of diabetes where
there is an insulin deficit and high
blood sugar. |
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How
does it manifest? |
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A
desire to eat frequently, and stomach
discomfort when hungry followed by
sweating, dizziness, confusion and
even fits and loss of consciousness
may be due to an insulinoma rather
than a form of epilepsy. These symptoms
can be avoided by frequent snacking
and are relieved by glucose. |
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How do you test for
it? |
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The
insulinoma can be easily diagnosed by checking
blood during such an episode or after a
few hours of starvation. The blood sugar
will be very low and the insulin level high.These
tumors are less than 15mm (1/2 inch) in
size and hence difficult to locate. Various
sophisticated scans, etc.,are used to locate
these tiny tumors. |
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How
is it treated? |
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In most
hospitals a major part of the pancreas is
removed surgically as the insulinoma is
too small to be identified by an inexperienced
surgeon. As Pancreas is a very important
organ for both digestion and preventing
diabetes, every effort should be made to
conserve it. A well defined insulinoma can
be easily removed without sacrificing the
pancreas provided it is identified. We are
able to identify and specifically remove
such an insulinoma even by laparoscopic
surgery so that the patient recovers rapidly
and returns to normal activity. If an insulinoma
is not well defined we localize it by the
various sophisticated methods listed earlier.
We have pioneered a method of conserving
the pancreas even in such patients. This
kind of minimal pancreas surgery avoids
converting a person from a state of excess
insulin (insulinoma) to a state of severe
insulin deficit (labile diabetes) which
is difficult to manage. Complications are
uncommon under the expert care of an experienced
surgeon.
Sometimes the problem may not be localized
(Nesidioblastosis) and a part of the pancreas
may have to be removed by open surgery.
Only about 10% of these tumors are cancers
and need extensive removal followed by anti
cancer medication. |
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What about Neuro
endocrine tumors other than Insulinoma?
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Other
Neuroendocrine tumors (a rare, distinct
group) include: Gastrinoma, Glucagonoma,
Somatostatinoma, VIPoma, Carcinoid, etc.
Most of them have fairly similar characteristics
in spite of the different hormones made
by them. These similarities include symptoms
like diarrhea, sweating, anxiety, headache,
fatigue etc.
Gastrinoma is tiny like an insulinoma
and the same tests are used to locate
it. Unlike other islet cell tumors it
often occurs outside the pancreas especially
in the duodenum (initial part of small
intestines). The surgery for it is similar
to that for insulinoma except that it
involves an extensive search even outside
the pancreas.
The tumors other than Gastrinoma are usually
large. Most are cancers requiring extensive
surgery and additional treatments like
hormone therapy, chemotherapy, biologic
therapy (immunotherapy), etc. |
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Adrenal
Tumors
(Pheochromocytoma, Conn’s syndrome / aldosteronOMA,
Cushing’s syndrome and Incidentalomas) |
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What are Adrenal
glands? |
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A
thumb sized, triangular shaped adrenal
gland is located on the top of each
of the two kidneys. They produce
hormones adrenaline, aldosterone
and cortisol. These hormones maintain
salt and water balance, control
blood pressure, stress responses,
and some sexual functions. |
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How does an
adrenal growth manifest itself? |
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High
blood pressure, headache, palpitations,
anxiety, weakness, fatigue, cramps,
tingling sensation, weak bones (osteoporosis),
Diabetes, overweight-obesity, infertility,streaks
on the abdomen, acne and facial
hair, can be caused by adrenal tumors.
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How do you detect
an Adrenal tumor? |
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Ultrasound, CT, MRI scans
can detect adrenal tumors. The tumor is
identified by testing urine and blood for
the hormones (and byproducts) produced by
it. Sometimes Isotope and PET scans or selective
venous sampling may be required to localize
them. |
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How is the tumor
removed? |
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Surgical
removal of the adrenal gland is called
adrenalectomy. This is best done by Laparoscopic
Surgery, thus facilitating early recovery
and return to normal activity. Large tumors
are removed by Hand Assisted Laparoscopic
Surgery or conventional open surgery.
Sometimes laparoscopic adrenalectomy is
not possible due to various factors and
the surgeon may decide on open surgery
either before or during the actual operation.
There are many ways of approaching the
adrenal in both laparoscopic & open
surgery. The backside and side approaches
are easier and faster but have certain
constraints. The front approach is tedious
but provides many more options. A specialist
endoscopic (laparoscopic) & endocrine
surgeon (a rare species!) would be conversant
with all these methods and approaches
and these technicalities are best left
to the specialist surgeon to decide. Urologists,
surgical oncologists, general surgeons,
laparoscopic surgeons also operate on
the adrenals, each by the method they
are familiar with. Complications are rare
if adequate preparations are done and
precautions taken under the expert care
of an experienced endocrine surgeon. |
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Disclamer:
This web site has been created for your
educational and informative needs. Any
and all communications are intended to
provide general information, and in no
way is a substitute for face-to-face medical
care. No implication of a doctor-patient
relationship should be assumed by the
reader. |
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